SCHEMBL1688137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1688142	0.90	KHK (0.50)	SLC6A2SLC6A4PDE10AEPHX2KHK
	SCHEMBL15160352	0.82	SLC6A2 (0.43)	SLC6A2SLC6A4PDE10ATDP1MAPT
	SCHEMBL16882199	0.78	SLC6A2 (0.43)	SLC6A2SLC6A4TDP1MAPTMAPK1
	SCHEMBL23555133	0.77	SLC6A2 (0.50)	SLC6A2SLC6A4TDP1MAPTMAPK1
	SCHEMBL3402972	0.77	CNR2 (0.42)	EPHX2SMN1; SMN2
	SCHEMBL15158792	0.77	SLC6A2 (0.40)	SLC6A2SLC6A4TDP1MAPTMAPK1
	SCHEMBL2940286	0.75	PDE10A (0.38)	PDE10ATDP1MAPTMAPK1GAA
	SCHEMBL21287875	0.75	ALDH1A1 (0.42)	SLC6A2SLC6A4TDP1MAPTMAPK1
	SCHEMBL23554912	0.75	SLC6A2 (0.38)	SLC6A2SLC6A4TDP1MAPTMAPK1
	SCHEMBL15495294	0.75	GRM2 (0.43)	TDP1MAPTMAPK1GAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.