Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080357 | 0.99 | ASAH1 (0.52) | ASAH1ACHEALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9774177 | 0.87 | ACHE (0.50) | ASAH1ACHE | |
| SCHEMBL17885899 | 0.83 | TPSAB1 (0.42) | ASAH1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9773935 | 0.82 | ACHE (0.47) | ASAH1ACHEALDH1A1 | |
| SCHEMBL4079691 | 0.81 | ALDH1A1 (0.48) | ASAH1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL17885925 | 0.81 | AKT1 (0.43) | HDAC8HDAC3HDAC1HDAC6 | |
| SCHEMBL9812894 | 0.81 | CYP3A4 (0.45) | ASAH1ACHEALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9847216 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL9773851 | 0.80 | TPSAB1 (0.54) | ACHEALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31655700 | 0.80 | TPSAB1 (0.54) | ACHEALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990511-A | Amide compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0353753-A1 | Amide compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-07 | — | — | EP | disclosed |