Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786068 | 0.91 | MTNR1A (0.48) | MTNR1ALMNAALDH1A1POLBHTT | |
| SCHEMBL9786073 | 0.90 | MTNR1A (0.47) | MTNR1ALMNAALDH1A1POLBHTT | |
| SCHEMBL9786082 | 0.89 | MTNR1A (0.46) | MTNR1ALMNAALDH1A1POLBHTT | |
| SCHEMBL32661221 | 0.78 | MTNR1A (0.51) | MTNR1ALMNAALDH1A1POLBHTT | |
| SCHEMBL19692664 | 0.78 | MTNR1A (0.51) | MTNR1ALMNAALDH1A1POLBHTT | |
| SCHEMBL7279369 | 0.75 | HPGD (0.57) | MTNR1ASMN1; SMN2MTNR1BTAAR1MEN1 | |
| SCHEMBL10382800 | 0.75 | HDAC3 (0.52) | MTNR1ALMNAALDH1A1POLBHTT | |
| Hydrochloric Acid SCHEMBL9786007 | 0.74 | LTA4H (0.45) | — | |
| Hydrochloric Acid SCHEMBL9786107 | 0.74 | LMNA (0.48) | LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL10382562 | 0.73 | HPGD (0.44) | MTNR1ALMNAALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023378-A | Hypotensive agents, antiischemic agents, urogenital disorders | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0188361-B1 | AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-03-06 | — | — | EP | disclosed |
| EP-0188361-A1 | Amine derivatives | GLAXO GROUP LIMITED (GB) | 1986-07-23 | — | — | EP | disclosed |