Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786587 | 0.83 | MAPT (0.50) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL9787252 | 0.71 | PDE4A (0.45) | LMNAMAPTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9786663 | 0.70 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9786605 | 0.66 | RAB9A (0.60) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL11738124 | 0.66 | MEN1 (0.62) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL10099725 | 0.65 | GAA (0.83) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL4737020 | 0.64 | MAOB (0.51) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL6302055 | 0.63 | GAA (0.64) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL20560273 | 0.62 | GAA (0.57) | LMNAMEN1KMT2APOLBGAA | |
| SCHEMBL4501719 | 0.62 | GAA (0.57) | LMNAMEN1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002961-A | Antiischemic Agents, Preventing Reperfusion Injuries | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-26 | — | — | US | disclosed |