Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786648 | 0.83 | LMNA (0.42) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7440158 | 0.76 | PDE4A (0.45) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL7339645 | 0.71 | PDE4A (0.67) | ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL9786655 | 0.71 | GAA (0.41) | GAA | |
| SCHEMBL10927097 | 0.67 | SLC22A12 (0.53) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL24430207 | 0.67 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10923793 | 0.67 | KMT2A (0.44) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9786585 | 0.66 | RAB9A (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11738124 | 0.65 | MEN1 (0.62) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10099725 | 0.64 | GAA (0.83) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002961-A | Antiischemic Agents, Preventing Reperfusion Injuries | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0312960-A2 | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-26 | — | — | EP | disclosed |