Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786606 | 0.77 | BRD4 (0.47) | KDM4ERXFP1 | |
| SCHEMBL9786655 | 0.77 | GAA (0.41) | KDM4E | |
| SCHEMBL7037055 | 0.66 | — | — | |
| SCHEMBL9629049 | 0.52 | GAA (0.46) | — | |
| SCHEMBL36504 | 0.52 | — | — | |
| SCHEMBL1694963 | 0.46 | — | — | |
| SCHEMBL3070619 | 0.46 | — | — | |
| SCHEMBL47369 | 0.46 | — | — | |
| SCHEMBL45851 | 0.46 | — | — | |
| Water SCHEMBL29512200 | 0.46 | ALDH1A1 (0.39) | KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002961-A | Antiischemic Agents, Preventing Reperfusion Injuries | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0312960-A2 | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-26 | — | — | EP | disclosed |