Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786663 | 0.77 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9786587 | 0.71 | MAPT (0.50) | GAA | |
| SCHEMBL3027360 | 0.69 | GAA (0.55) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL5419895 | 0.68 | GAA (0.46) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL29323664 | 0.67 | NSD2 (0.44) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL9786590 | 0.67 | L3MBTL1 (0.48) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL10807868 | 0.65 | NSD2 (0.43) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL9786600 | 0.64 | NSD2 (0.42) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL10804145 | 0.64 | L3MBTL1 (0.59) | GAANSD2ABL1IDERIN1 | |
| SCHEMBL9786577 | 0.64 | L3MBTL1 (0.46) | GAANSD2ABL1IDERIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002961-A | Antiischemic Agents, Preventing Reperfusion Injuries | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0312960-A2 | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-26 | — | — | EP | disclosed |