Biphenyl

Biphenyl

SCHEMBL9787041

O=C(COCC(=O)c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.58
TDP1 Q9NUW8 3/20 0.58
SMN1; SMN2 Q16637 5/20 0.54
MAPT P10636 5/20 0.54
HPGD P15428 3/20 0.54
MAPK1 P28482 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.54
CYP3A4 P08684 1/20 0.54
ALOX15 P16050 1/20 0.54
CES1 P23141 1/20 0.54
KMT2A Q03164 1/20 0.54
GSK3B P49841 3/20 0.53
PTPN1 P18031 2/20 0.53
LMNA P02545 3/20 0.53
RAB9A P51151 4/20 0.52
HIF1A Q16665 2/20 0.52
CYP1A2 P05177 2/20 0.52
FFAR1 O14842 1/20 0.52
ALDH1A1 P00352 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28761949 0.94 MAPT (0.62) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
SCHEMBL864716 0.93 MAPT (0.61) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
SCHEMBL3194897 0.87 TDP1 (0.54) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
Biphenyl SCHEMBL9787298 0.87 L3MBTL1 (0.63) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
Hydroquinone SCHEMBL9786967 0.85 CES2 (0.54) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
Phenol SCHEMBL11815882 0.85 TDP1 (0.52) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
Catechol SCHEMBL9787047 0.85 ESR1 (0.57) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
SCHEMBL3216220 0.83 L3MBTL1 (0.51) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
SCHEMBL3136962 0.83 TDP1 (0.54) L3MBTL1TDP1SMN1; SMN2MAPTHPGD
SCHEMBL6963661 0.81 SMN1; SMN2 (0.54) L3MBTL1TDP1SMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US claimed
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed