Hydroquinone

Hydroquinone

SCHEMBL9786967

O=C(COCC(=O)c1ccccc1)c1ccccc1.Oc1ccc(O)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.54
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPK1 P28482 2/20 0.52
HPGD P15428 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
CES1 P23141 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
RAB9A P51151 4/20 0.48
LMNA P02545 1/20 0.48
ALDH1A1 P00352 3/20 0.48
GSK3B P49841 2/20 0.48
TRPA1 O75762 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL11815882 0.96 TDP1 (0.52) CES2MAPTMEN1KMT2AMAPK1
SCHEMBL864716 0.91 MAPT (0.61) MAPTMEN1KMT2AMAPK1HPGD
SCHEMBL14735749 0.89 NPC1 (0.58) MAPTTDP1KDM4EESR1ESR2
Catechol SCHEMBL9787047 0.88 ESR1 (0.57) MAPTMEN1KMT2AMAPK1HPGD
Resorcinol SCHEMBL9786972 0.86 ESR1 (0.53) MAPTMEN1KMT2AMAPK1HPGD
SCHEMBL3194897 0.85 TDP1 (0.54) MAPTMEN1KMT2AMAPK1HPGD
Biphenyl SCHEMBL9787041 0.85 L3MBTL1 (0.58) MAPTMEN1KMT2AMAPK1HPGD
SCHEMBL9787020 0.82 NPC1 (0.66) MAPTMEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL3216220 0.82 L3MBTL1 (0.51) MAPTMEN1KMT2AMAPK1HPGD
SCHEMBL657234 0.82 TDP1 (0.55) MAPTMEN1KMT2AMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed