Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183115 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL16714723 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL12215278 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL4139311 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL4139305 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL9472620 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL5599045 | 0.87 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL16714801 | 0.85 | ALDH1A1 (0.58) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL27959247 | 0.82 | KMT2A (0.51) | ASAH1ALDH1A1ACER2MEN1FAAH | |
| SCHEMBL22060063 | 0.82 | NR1H4 (0.56) | ALDH1A1MEN1KMT2ANR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | claimed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | claimed |
| US-5002703-A | Benzoic acid and benzoic acid ester derivatives having antiinflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4990533-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT CO. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4980095-A | Sodium salt of N-C4-carboxybenzyl nonanamide | WARNER-LAMBERT COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4771064-A | Benzoic acid and benzoic acid ester derivatives having antiflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| US-4755518-A | Imidazolyl or tetrazolyl substituted benzoic acid derivatives and pharmaceutical compositions thereof | WARNER-LAMBERT COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4719232-A | Benzoic acid and benzoic acid ester derivatives to treat headaches | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719234-A | Benzoic acid and benzoic acid ester derivatives to treat inflammation | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719233-A | Benzoic acid and benzoic acid ester derivatives to treat pain | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |