Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.55 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015319 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL15200212 | 0.87 | ACACA (0.57) | ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16714723 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL5599045 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL12215278 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL9472620 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL4139305 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL4183115 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL4139311 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1FAAHMAPK1 | |
| SCHEMBL9787232 | 0.85 | ASAH1 (0.56) | ALDH1A1MEN1FAAHMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150140588-A1 | Lipase Variants and Polynucleotides Encoding Same | NOVOZYMES A/S (DK) | 2015-05-21 | — | — | US | disclosed |