Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684128 | 1.00 | ADRB3 (0.55) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11244639 | 0.88 | ADRB2 (0.60) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11573996 | 0.88 | ADRB2 (0.60) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11244640 | 0.88 | ADRB2 (0.60) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11456005 | 0.88 | ADRB2 (0.60) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| Hydrochloric Acid SCHEMBL11107885 | 0.83 | HTR1A (0.46) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| Maleic Acid SCHEMBL11575619 | 0.82 | KMT2A (0.53) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11456001 | 0.81 | ADRB2 (0.56) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11456002 | 0.81 | ADRB2 (0.56) | ADRB3ADRB2ADRB1MAPTHTR7 | |
| SCHEMBL11246083 | 0.81 | ADRB2 (0.56) | ADRB3ADRB2ADRB1MAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |