Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787733 | 0.82 | KMT2A (0.64) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9787808 | 0.81 | ACACB (0.57) | ALDH1A1 | |
| SCHEMBL9439608 | 0.79 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9AMAPT | |
| Acetic Acid SCHEMBL9787824 | 0.77 | NPC1 (0.48) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9787815 | 0.75 | MAPT (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6597221 | 0.73 | PLA2G4B (0.57) | SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL9787734 | 0.73 | ESRRG (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29926191 | 0.72 | LMNA (0.74) | LMNA | |
| SCHEMBL9439602 | 0.72 | SMN1; SMN2 (0.52) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9787730 | 0.71 | MAPT (0.44) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |