Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787815 | 0.80 | MAPT (0.45) | MAPTLMNATP53KMT2ANPC1 | |
| SCHEMBL9439608 | 0.76 | KMT2A (0.53) | MAPTLMNAKMT2AGLANPC1 | |
| SCHEMBL9787773 | 0.74 | TBXAS1 (0.57) | SMN1; SMN2ACACBALDH1A1HPGDLTA4H | |
| SCHEMBL9787733 | 0.73 | KMT2A (0.64) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9787729 | 0.71 | KMT2A (0.53) | MAPTLMNATP53KMT2ANPC1 | |
| SCHEMBL9787748 | 0.71 | LMNA (0.43) | MAPTLMNATP53KMT2AGLA | |
| SCHEMBL9439602 | 0.69 | SMN1; SMN2 (0.52) | LMNAKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9787721 | 0.69 | KMT2A (0.41) | MAPTKMT2AGLANPC1RAB9A | |
| Acetic Acid SCHEMBL9787824 | 0.68 | NPC1 (0.48) | MAPTLMNATP53KMT2ANPC1 | |
| SCHEMBL2779430 | 0.68 | PKM (0.46) | LMNAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |