Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787726 | 0.81 | NPC1 (0.42) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL9787729 | 0.73 | KMT2A (0.53) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL9439608 | 0.73 | KMT2A (0.53) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL9787733 | 0.70 | KMT2A (0.64) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| Acetic Acid SCHEMBL9787824 | 0.69 | NPC1 (0.48) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL23668225 | 0.68 | KDM4E (0.63) | MAPTALDH1A1GAA | |
| SCHEMBL9787767 | 0.68 | ACACB (0.58) | NPC1ACACB | |
| SCHEMBL25210517 | 0.68 | THRA (0.43) | L3MBTL1SMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL5195144 | 0.67 | THRA (0.48) | L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL13913241 | 0.66 | ALDH1A1 (0.65) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |