Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535645 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL5451 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL31546843 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL30283197 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL544603 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| Hydrochloric Acid SCHEMBL27764098 | 0.74 | NPC1 (0.50) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL5243360 | 0.74 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.73 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.73 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1NPSR1MAPTGLA | |
| SCHEMBL10467741 | 0.72 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1NPSR1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |