Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787721 | 0.82 | KMT2A (0.41) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9787823 | 0.80 | TP53 (0.42) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9787812 | 0.79 | KMT2A (0.44) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9439608 | 0.76 | KMT2A (0.53) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| Oxalic Acid SCHEMBL9787761 | 0.75 | ADRB3 (0.45) | LMNAHTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9492908 | 0.75 | ADRB3 (0.42) | LMNAHTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9787709 | 0.72 | ADRB3 (0.47) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1432886 | 0.71 | MMP8 (0.45) | NPC1MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9787730 | 0.71 | MAPT (0.44) | LMNAHTTNPC1RAB9AMAPT | |
| SCHEMBL9439602 | 0.69 | SMN1; SMN2 (0.52) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |