Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787808 | 0.76 | ACACB (0.57) | ACACB | |
| SCHEMBL9782119 | 0.76 | ACACB (0.72) | ACACB | |
| SCHEMBL256292 | 0.75 | ACACB (0.82) | ACACB | |
| SCHEMBL11998669 | 0.73 | ACACB (1.00) | ACACB | |
| SCHEMBL10636765 | 0.70 | ACACB (0.64) | ACACB | |
| SCHEMBL10636768 | 0.70 | ACACB (0.64) | ACACB | |
| SCHEMBL9787803 | 0.68 | ACACB (0.63) | ACACB | |
| SCHEMBL9787734 | 0.68 | ESRRG (0.49) | ACACBNPC1 | |
| SCHEMBL11686920 | 0.68 | ACACB (0.63) | ACACB | |
| SCHEMBL8881007 | 0.67 | ACACB (0.58) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |