Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.74 |
| ▸ | CASP7 | P55210 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304367 | 0.86 | KMT2A (0.62) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL29416517 | 0.86 | KMT2A (0.62) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL29709713 | 0.86 | KMT2A (0.62) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL2354794 | 0.85 | MAOA (1.00) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL41161 | 0.85 | MAOA (1.00) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL29398266 | 0.85 | MAOA (1.00) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL29358061 | 0.85 | MAOA (1.00) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Water SCHEMBL28602073 | 0.84 | KMT2A (0.60) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL4560050 | 0.83 | MAOA (0.95) | MAOAKDM4EALDH1A1SMN1; SMN2GLA | |
| Xanthone SCHEMBL18556112 | 0.83 | MAOA (0.95) | MAOAKDM4EALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7374749-B2 | Amino substituted hydroxyphenyl benzophenone derivatives | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7374749-B2 | Amino substituted hydroxyphenyl benzophenone derivatives | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-05-20 | — | — | US | disclosed |
| US-5057590-A | Bislactone curing agents for epoxy resins and polymers obtained therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1991-10-15 | — | — | US | disclosed |