Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Afloqualone SCHEMBL400184 | 0.84 | PDE4D (1.00) | PDE4DMAPTALDH1A1KDM4EHPGD | |
| Afloqualone SCHEMBL29540781 | 0.84 | PDE4D (1.00) | PDE4DMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4959299 | 0.82 | LMNA (0.63) | PDE4DMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL10735755 | 0.79 | PDE4D (0.83) | PDE4DMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10739746 | 0.78 | PDE4D (0.77) | PDE4DMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10742868 | 0.77 | PDE4D (0.76) | PDE4DMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10741182 | 0.77 | PDE4D (0.76) | PDE4DNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL15818541 | 0.76 | HTR7 (0.50) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10737618 | 0.76 | PDE4D (0.74) | PDE4DMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL10709171 | 0.76 | PDE4D (0.74) | PDE4DMAPTNPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3058977-A | — | — | None | — | — | JP | disclosed |
| JP-H0358977-A | PRODUCTION OF QUINAZOLINONE DERIVATIVE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1991-03-14 | — | — | JP | disclosed |