Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL927251 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL28174378 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL8347193 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL428821 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL5083280 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL29391743 | 0.98 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL10861143 | 0.94 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL10686337 | 0.94 | CA1 (0.42) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27529151 | 0.93 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22800845 | 0.91 | CA1 (0.52) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7807 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115108-A1 | COMPOSITIONS IN THE FORM OF DISSOLVABLE SOLID STRUCTURES | PROCTER & GAMBLE (US) | 2026-04-30 | — | — | US | claimed |
| EP-4615945-A1 | HOME CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2025-09-17 | — | — | EP | claimed |
| WO-2025084522-A1 | METHOD AND APPARATUS FOR MANUFACTURING LITHIUM CERAMIC PEBBLES FOR TRITIUM BREEDING MATERIALS | 가천대학교 산학협력단 | 2025-04-24 | — | — | WO | claimed |
| US-12215298-B2 | Single chamber water-soluble refill dose article enclosing a concentrated cleanser composition and kits having same | HAYDEN PRODUCTS LLC (US) | 2025-02-04 | — | — | US | claimed |
| US-20250025380-A1 | PERSONAL CARE DISSOLVABLE SHEET, COMPOSITIONS, METHODS OF MAKING AND USING THE SAME | IPX, LLC (US) | 2025-01-23 | — | — | US | claimed |
| CN-118767648-A | System for storing carbon dioxide, application and carbon dioxide storage and transportation method | 中国石油化工股份有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-12057585-B2 | Conductive composition for secondary battery | GRST INTERNATIONAL LIMITED (CN) | 2024-08-06 | — | — | US | claimed |
| CN-118401645-A | Household care composition | 高露洁-棕榄公司 | 2024-07-26 | — | — | CN | claimed |
| EP-4245296-B1 | COMPOSITIONS IN THE FORM OF DISSOLVABLE SOLID STRUCTURES | PROCTER & GAMBLE (US) | 2024-07-17 | — | — | EP | claimed |
| EP-4392521-A1 | HOME CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2024-07-03 | — | — | EP | claimed |
| EP-0344220-A1 | COLD STABLE LIQUID CREATININE REAGENT. | BECKMAN INSTRUMENTS INC (US) | 1989-12-06 | — | — | EP | claimed |
| WO-1988010429-A1 | COLD STABLE LIQUID CREATININE REAGENT | BECKMAN INSTRUMENTS, INC. (US) | 1988-12-29 | — | — | WO | claimed |
| EP-0294894-A2 | Conditioning agents and compositions containing same | THE PROCTER & GAMBLE COMPANY (US) | 1988-12-14 | — | — | EP | claimed |
| EP-0294893-A2 | Conditioning agents and compositions containing same | THE PROCTER & GAMBLE COMPANY (US) | 1988-12-14 | — | — | EP | claimed |
| US-4741782-A | FLY ASH | RESOURCE TECHNOLOGY, INC. (US) | 1988-05-03 | — | — | US | claimed |
| US-4487658-A | Aqueous neutralizing and lubricating composition for diesel engines | AGIP PETROLI S.P.A (IT) | 1984-12-11 | — | — | US | claimed |
| US-4272495-A | Chemical processes | WOODSREEF MINES LIMITED (AU) | 1981-06-09 | — | — | US | claimed |
| US-4246131-A | BETAINE SURFACTANT AND AMINE FATTY ALCOHOL SULFATE OR SULFONATE SHAMPOO COMPOSITION | INOLEX CORPORATION (US) | 1981-01-20 | — | — | US | claimed |
| US-4165293-A | Solid transparent cleanser | AMWAY CORPORATION (US) | 1979-08-21 | — | — | US | claimed |
| US-4137191-A | Low-irritant surfactant composition | INOLEX CORPORATION (US) | 1979-01-30 | — | — | US | claimed |