Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL97879 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL927251 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL28174378 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL8347193 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL428821 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL29391743 | 0.98 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL10861143 | 0.94 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| Diethanolamine SCHEMBL10686337 | 0.94 | CA1 (0.42) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27529151 | 0.93 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22800845 | 0.91 | CA1 (0.52) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | BEAUTY BIOLABS LLC (US) | 2026-05-19 | — | — | US | disclosed |
| WO-2026087745-A1 | AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE | BRAIN Biotech AG (DE) | 2026-04-30 | — | — | WO | disclosed |
| EP-4732825-A1 | AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE | BRAIN Biotech AG (DE) | 2026-04-29 | — | — | EP | disclosed |
| US-20260096978-A1 | A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS | SYMRISE AG (DE) | 2026-04-09 | — | — | US | disclosed |
| EP-4025675-B1 | A PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2026-03-18 | — | — | EP | disclosed |
| EP-3837018-B1 | SULFATE-FREE COSMETIC RINSE-OFF COMPOSITION COMPRISING A HYPERBRANCHED COPOLYMER | DSM IP ASSETS BV (NL) | 2026-02-25 | — | — | EP | disclosed |
| US-20260047994-A1 | AN ACTIVE COMPOSITION COMPRISING RETINOL | SYMRISE AG (DE) | 2026-02-19 | — | — | US | disclosed |
| US-20260041094-A1 | Compositions Comprising an Antimicrobial Boosting Agent | SYMRISE AG (DE) | 2026-02-12 | — | — | US | disclosed |
| EP-4687810-A1 | PREPARATIONS COMPRISING HYDROXY PINACOLONE RETINOATE | Symrise AG (DE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4110276-B1 | COMPOSITIONS COMPRISING ALKANEDIOLS | SYMRISE AG (DE) | 2026-01-28 | — | — | EP | disclosed |
| CN-1247699-C | Polyorganosiloxane emulsion, process for producing the same, and material for cosmetic preparation | DOW CORNING TORAY SILICONE (JP) | 2006-03-29 | — | — | CN | disclosed |
| EP-1541633-A1 | AQUEOUS SUSPENSION OF CROSSLINKED SILICONE PARTICLES, AQUEOUS EMULSION OF OIL CONTAINING CROSSLINKED SILICONE PARTICLES, AND COSMETIC INGREDIENTS | Dow Corning Toray Silicone Company, Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20040147647-A1 | Polyorganosiloxane micro-emulsion composition and raw material for cosmetics | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2004-07-29 | — | — | US | disclosed |
| US-20040138373-A1 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOW TORAY CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| CN-1505663-A | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | ������������ʽ���� | 2004-06-16 | — | — | CN | disclosed |
| US-20040091438-A1 | Polyorganosiloxane emulsions,process for producing the same and material for cosmetic preparation | DOW CORNING TORAY SILICONE CO. LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| CN-1496387-A | Polyorganosiloxane emulsion, process for producing the same, and material for cosmetic preparation | 陶氏康宁东丽硅氧烷株式会社 | 2004-05-12 | — | — | CN | disclosed |
| EP-1406575-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1394215-A1 | POLYORGANOSILOXANE EMULSION, PROCESS FOR PRODUCING THE SAME, AND MATERIAL FOR COSMETIC PREPARATION | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002094213-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | DOW CORNING TORAY SILICONE CO.,LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | KRT18, HCN4, COL14A1 | CA1 455/4885CA2 154/4885CA9 1378/4885 |
| US-20040091438-A1 | Polyorganosiloxane emulsions,process for producing the same and material for cosmetic preparation | CUTA, UNG, PCNA | CA1 3951/4885CA2 4091/4885CA9 3606/4885 |
| US-20260041094-A1 | Compositions Comprising an Antimicrobial Boosting Agent | TLR7, MYC, ERG28 | CA1 4875/4885CA2 4525/4885CA9 4679/4885 |
| US-20260047994-A1 | AN ACTIVE COMPOSITION COMPRISING RETINOL | RBP4, LRAT, RARB | CA1 1939/4885CA2 1876/4885CA9 2547/4885 |
| US-20260096978-A1 | A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS | PTGS2, PTGES2, PTGS1 | CA1 1298/4885CA2 332/4885CA9 781/4885 |
| US-20040147647-A1 | Polyorganosiloxane micro-emulsion composition and raw material for cosmetics | UNG, PHOSPHO1, TPMT | CA1 3135/4885CA2 3796/4885CA9 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.