Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22203778 | 0.80 | CA2 (0.56) | POLBCYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL14667522 | 0.77 | G6PC1 (0.57) | LMNAPOLBCYP1A2ALDH1A1GAA | |
| SCHEMBL2615559 | 0.77 | G6PC1 (0.57) | LMNAPOLBCYP1A2ALDH1A1GAA | |
| SCHEMBL265248 | 0.75 | LMNA (0.57) | LMNAPOLBCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2185353 | 0.75 | LMNA (0.57) | LMNAPOLBCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5958167 | 0.74 | GAA (0.40) | ALDH1A1GAAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL5958164 | 0.74 | GAA (0.40) | ALDH1A1GAAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL18015095 | 0.74 | GAA (0.43) | GAAMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL22260021 | 0.73 | MAOB (0.45) | LMNAALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL6734905 | 0.73 | LMNA (0.61) | LMNAPOLBCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985582-A | CHEMICAL INTERMEDIATES FOR BICYCLIC RING COMPOUNDS HAVING MULTIPLE SULFUR ATOMS IN THE RING SYSTEM | THE WELLCOME FOUNDATION LTD. (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0216625-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |