Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 3/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788337 | 0.81 | NR4A3 (0.50) | MAPK1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10357432 | 0.80 | CCNE2 (0.42) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL9788312 | 0.80 | RAB9A (0.40) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL10812124 | 0.79 | SRC (0.44) | CDK4CCND1MAPK1SRCKDR | |
| SCHEMBL9788299 | 0.76 | MAPK14 (0.46) | MAPK1MEN1KMT2ASMN1; SMN2MAPK14 | |
| SCHEMBL9788296 | 0.69 | NR4A3 (0.46) | SRCKDRMEN1KMT2AHPGD | |
| SCHEMBL9005822 | 0.68 | NR4A3 (0.51) | KMT2ASMN1; SMN2LMNAPKM | |
| SCHEMBL9788273 | 0.66 | NR4A3 (0.67) | MAPK1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL122191 | 0.66 | NR4A3 (0.51) | MAPK1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL9005800 | 0.64 | MAPT (0.51) | MAPK1MEN1KMT2ANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |