Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788299 | 0.91 | MAPK14 (0.46) | NR4A3POLBSMN1; SMN2MAPK14MAPT | |
| SCHEMBL9788273 | 0.84 | NR4A3 (0.67) | NR4A3KEAP1NFE2L2HPGDPOLB | |
| SCHEMBL9788253 | 0.82 | NR4A3 (0.56) | NR4A3KEAP1NFE2L2POLBMAPK14 | |
| SCHEMBL9788259 | 0.81 | CCNE2 (0.41) | HPGDPOLBSMN1; SMN2MAPK14L3MBTL1 | |
| SCHEMBL9788244 | 0.80 | NR4A3 (0.53) | NR4A3KEAP1NFE2L2POLBSMN1; SMN2 | |
| SCHEMBL9788312 | 0.77 | RAB9A (0.40) | POLBMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL10712738 | 0.76 | POLB (0.46) | HPGDPOLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9788240 | 0.76 | MAPK1 (0.58) | NR4A3HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9788264 | 0.75 | CYP2C9 (0.57) | NR4A3KEAP1NFE2L2POLBSMN1; SMN2 | |
| SCHEMBL9005834 | 0.73 | NR4A3 (0.52) | NR4A3TP53POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |