Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CFB | P00751 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788321 | 0.86 | TAAR1 (0.48) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788294 | 0.84 | ADRA2A (0.40) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788281 | 0.84 | ADRA2A (0.40) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL7044957 | 0.84 | TAAR1 (0.48) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788291 | 0.83 | TAAR1 (0.45) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788311 | 0.80 | TAAR1 (0.55) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788289 | 0.79 | ADRA2A (0.40) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788263 | 0.77 | CFB (0.41) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788340 | 0.77 | CFB (0.50) | ADRA2AADRA2CADRA1AADRA2BTAAR1 | |
| SCHEMBL9788317 | 0.77 | CFB (0.44) | ADRA2AADRA2CADRA1AADRA2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |