SCHEMBL9788362

SCHEMBL9788362

Cc1ccccc1CNC(=O)CNC(=O)C1(C)CC1(Cl)Cl

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAOK1 Q7L7X3 1/20 0.51
TAOK3 Q9H2K8 1/20 0.51
ALDH1A1 P00352 4/20 0.48
HPGD P15428 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 2/20 0.43
HTT P42858 1/20 0.43
P2RX7 Q99572 2/20 0.43
PKM P14618 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509533 0.83 SMN1; SMN2 (0.48) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL9508402 0.80 KMT2A (0.50) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL9788342 0.78 RAB9A (0.46) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL9788334 0.77 MEN1 (0.53) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL9788335 0.75 TAAR1 (0.47) HPGDSMN1; SMN2GAANPSR1KDM4E
SCHEMBL3022726 0.73 ALDH1A1 (0.62) TAOK1TAOK3ALDH1A1HPGDSMN1; SMN2
SCHEMBL24576210 0.72 ALDH1A1 (0.68) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL30259908 0.71 ALDH1A1 (0.64) TAOK1TAOK3ALDH1A1HPGDSMN1; SMN2
SCHEMBL13170238 0.71 ALDH1A1 (0.64) TAOK1TAOK3ALDH1A1HPGDSMN1; SMN2
SCHEMBL5144070 0.71 ALDH1A1 (0.64) TAOK1TAOK3ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034408-A Fungicides of dihalocyclopropanoylamino acid amides BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US claimed