Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712312 | 0.86 | DRD2 (0.57) | DRD2DRD1DRD3KDM4EALDH1A1 | |
| SCHEMBL10593191 | 0.85 | PTPN1 (0.50) | DRD2DRD1DRD3KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL10527368 | 0.84 | PTPN1 (0.49) | DRD2DRD1DRD3KDM4ETDP1 | |
| SCHEMBL21741610 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9788511 | 0.80 | ALDH1A1 (0.52) | DRD2DRD1DRD3KDM4EALDH1A1 | |
| SCHEMBL9788507 | 0.79 | ABCB1 (0.52) | GAAMEN1KMT2AABCB1HRH3 | |
| Hydrochloric Acid SCHEMBL9788535 | 0.79 | ALDH1A1 (0.51) | DRD2DRD1DRD3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7628740 | 0.79 | GCGR (0.60) | KDM4EGCGRGAAPOLBHRH3 | |
| SCHEMBL8401002 | 0.78 | DRD2 (0.75) | DRD2DRD1DRD3KDM4EALDH1A1 | |
| SCHEMBL11365759 | 0.78 | DRD2 (0.75) | DRD2DRD1DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015663-A | Treatment of conditions requiring enhanced oxygen availability of mammalian tissues | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-05-14 | — | — | US | claimed |