Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689543 | 0.83 | CYP11B2 (0.43) | MAPTMAPK1 | |
| SCHEMBL25070257 | 0.81 | ALDH1A1 (0.40) | NPC1RAB9AMAPTTDP1LMNA | |
| SCHEMBL29178034 | 0.76 | MET (0.39) | METNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28241225 | 0.76 | MET (0.39) | METNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL21285405 | 0.76 | MEN1 (0.47) | SMN1; SMN2HPGDMEN1KMT2AMAPT | |
| SCHEMBL21258588 | 0.73 | PLD1 (0.41) | METNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1396722 | 0.73 | HSD17B10 (0.38) | METSIGMAR1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30672489 | 0.72 | HSD17B10 (0.37) | METSIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27878088 | 0.72 | MET (0.36) | METNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28308636 | 0.72 | MET (0.36) | METNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992768-B | The Imidazopyridazine compounds of conditioning agent as the response of IL 12, IL 23 and/or IFN α | 百时美施贵宝公司 | 2018-04-20 | — | — | CN | disclosed |
| US-5026846-A | Process for the preparation of diaryl sulphides and diaryl selenides | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |