Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425400 | 0.90 | DRD2 (0.44) | DRD2HTR2AKDM4EALDH1A1MAPT | |
| SCHEMBL7332157 | 0.84 | DRD2 (0.57) | DRD2HTR2AHRH4HTTCYP1A2 | |
| SCHEMBL7327599 | 0.83 | DRD2 (0.55) | DRD2HTR2AHRH4HTTCYP1A2 | |
| SCHEMBL7333157 | 0.73 | DRD2 (0.93) | DRD2HTR2AHRH4HTTCYP1A2 | |
| Blonanserin SCHEMBL119669 | 0.72 | DRD2 (1.00) | DRD2HTR2AHRH4HTTCYP1A2 | |
| SCHEMBL7334897 | 0.72 | DRD2 (1.00) | DRD2HTR2AHRH4HTTCYP1A2 | |
| Blonanserin SCHEMBL29379647 | 0.72 | DRD2 (1.00) | DRD2HTR2AHRH4HTTCYP1A2 | |
| SCHEMBL9440217 | 0.72 | DRD2 (0.63) | DRD2HTR2AHRH4HTTCYP1A2 | |
| Blonanserin SCHEMBL28204389 | 0.72 | DRD2 (0.98) | DRD2HTR2AHRH4HTTCYP1A2 | |
| Blonanserin SCHEMBL28331931 | 0.72 | DRD2 (0.98) | DRD2HTR2AHRH4HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |