Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.58 |
| ▸ | ALB | P02768 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385117 | 0.94 | GABRA1 (0.66) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL10384385 | 0.89 | GABRB2 (0.57) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| Necopidem SCHEMBL1061121 | 0.89 | GABRA1 (0.57) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL10467508 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL9788663 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL10761650 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL9788668 | 0.86 | GABRA1 (0.54) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL9788698 | 0.86 | GABRA1 (0.53) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL9788667 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL10467219 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2ALBOPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990506-A | Sedatives, anxiolytic, antiulcer, antistress | SYNTHELABO (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4767755-A | NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1988-08-30 | — | — | US | disclosed |