SCHEMBL9788901

SCHEMBL9788901

O=c1c2ccc(c(=O)n1CCCc1ccccc1)c1c3ccc(c(=O)n(CCCc4ccccc4)c3=O)c21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.51
GSK3B P49841 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
ADORA2B P29275 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
FAAH O00519 1/20 0.46
MGLL Q99685 1/20 0.46
CNOT7 Q9UIV1 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
G6PD P11413 1/20 0.45
MAPK8 P45983 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21894139 0.73 CYP1B1 (0.67) GSK3AGSK3BL3MBTL1LMNAALDH1A1
SCHEMBL7983612 0.72 SRC (0.70) L3MBTL1LMNAALDH1A1MEN1KMT2A
SCHEMBL17278442 0.72 SIGMAR1 (0.62) SIGMAR1
SCHEMBL6075628 0.72 TDP1 (0.61) L3MBTL1ALDH1A1ADORA2BTDP1FAAH
SCHEMBL6075749 0.70 TDP1 (0.59) L3MBTL1ALDH1A1ADORA2BTDP1FAAH
SCHEMBL15057066 0.70 TDP1 (0.59) L3MBTL1ALDH1A1ADORA2BTDP1FAAH
SCHEMBL6751129 0.70 TDP1 (0.42) L3MBTL1ALDH1A1TDP1GAA
SCHEMBL24709343 0.69 CACNA1G (0.62) GSK3AGSK3BL3MBTL1LMNAALDH1A1
SCHEMBL6076720 0.69 TDP1 (0.52) L3MBTL1ALDH1A1ADORA2BTDP1GAA
SCHEMBL3380286 0.68 GSK3A (1.00) GSK3AGSK3BL3MBTL1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992349-A Cyclic bis-dicarboximide charge transport compounds for electrophotography EASTMAN KODAK COMPANY (US) 1991-02-12 US claimed
EP-0119755-B1 SENSITIZED PHOTOCONDUCTIVE COMPOSITIONS AND ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-12-02 EP claimed
EP-0119755-A2 Sensitized photoconductive compositions and elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-09-26 EP claimed
US-4468444-A Pyrylium-sensitized leuco base photoconductive compositions and elements containing naphthalene bis-dicarboximide compounds EASTMAN KODAK COMPANY (US) 1984-08-28 US claimed
US-4442193-A SENSITIZED TO RADIATION BELOW 400 NANOMETERS EASTMAN KODAK COMPANY (US) 1984-04-10 US claimed
US-4992349-A Cyclic bis-dicarboximide charge transport compounds for electrophotography EASTMAN KODAK COMPANY (US) 1991-02-12 US disclosed
EP-0186172-B1 ELECTROPHOTOGRAPHIC COLOR PROOFING METHOD EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-07-19 EP disclosed
US-4686163-A Electrophotographic color imaging method EASTMAN KODAK COMPANY (US) 1987-08-11 US disclosed
US-4600669-A Electrophotographic color proofing element and method for using the same EASTMAN KODAK COMPANY (US) 1986-07-15 US disclosed
EP-0186172-A1 Electrophotographic color proofing method EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-02 EP disclosed
US-4468444-A Pyrylium-sensitized leuco base photoconductive compositions and elements containing naphthalene bis-dicarboximide compounds EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed