SCHEMBL9788942

SCHEMBL9788942

CC(Br)C(=O)c1c[nH]c2ccc(Cl)cc12

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 1/20 0.65
▸ F3 P13726 1/20 0.65
▸ NR4A2 P43354 1/20 0.61
▸ PYGL P06737 1/20 0.52
▸ NHERF1 O14745 4/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30457940 1.00 F7 (0.65) F7F3NR4A2PYGLNHERF1
SCHEMBL24067322 0.88 F7 (0.69) F7F3NR4A2PYGLNHERF1
SCHEMBL25261694 0.84 NR4A2 (0.62) NR4A2ALDH1A1KMT2A
SCHEMBL26261524 0.83 NR4A2 (0.62) F7F3NR4A2PYGLNHERF1
SCHEMBL26261554 0.83 NR4A2 (0.62) F7F3NR4A2PYGLNHERF1
SCHEMBL25259281 0.83 NR4A2 (0.62) F7F3NR4A2PYGLNHERF1
SCHEMBL30457844 0.83 NR4A2 (0.62) F7F3NR4A2PYGLNHERF1
SCHEMBL25305847 0.82 KDM4E (0.55) NR4A2ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL25306279 0.82 NR4A2 (0.60) F7F3NR4A2PYGLNHERF1
SCHEMBL25742072 0.80 NR4A2 (0.58) F7F3NR4A2PYGLNHERF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 — — EP disclosed
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-08-17 — — US disclosed
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-08-17 — — US disclosed
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-08-17 — — US disclosed
EP-4214192-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT Tactogen Inc. (US) 2023-07-26 — — EP disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 — — WO disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 — — WO disclosed
WO-2022061242-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2022-03-24 — — WO disclosed
EP-0259085-B1 2-GUANIDINO-4-ARYLTHIAZOLES FOR TREATMENT OF PEPTIC ULCERS PFIZER INC. (US) 1991-08-21 — — EP disclosed
US-5026715-A 2-guanidino-4-arylthiazoles for treatment of peptic ulcers PFIZER INC. (US) 1991-06-25 — — US disclosed
EP-0259085-A1 2-Guanidino-4-arylthiazoles for treatment of peptic ulcers PFIZER INC. (US) 1988-03-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT HTR6, TPH2, TPH1 F7 1035/4885F3 2087/4885NR4A2 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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