Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788947 | 0.89 | KLKB1 (0.49) | KLKB1LMNAKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL9788986 | 0.84 | KLKB1 (0.48) | KLKB1LMNAKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL9788970 | 0.81 | LMNA (0.56) | KLKB1LMNAKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL1156845 | 0.81 | TSHR (0.51) | KLKB1LMNAKMT2AMAPK1HSD17B10 | |
| SCHEMBL9789023 | 0.75 | KLKB1 (0.45) | KLKB1LMNAKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL15561093 | 0.72 | TSHR (0.50) | LMNAKMT2AGAAMAPK1HSD17B10 | |
| SCHEMBL1156730 | 0.72 | HTR6 (0.46) | KLKB1LMNAKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL27233758 | 0.69 | LMNA (0.64) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL4962809 | 0.69 | TSHR (0.47) | LMNAKMT2AMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL1156250 | 0.68 | KDM4E (0.50) | LMNAKMT2AHTR6MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026715-A | 2-guanidino-4-arylthiazoles for treatment of peptic ulcers | PFIZER INC. (US) | 1991-06-25 | — | — | US | disclosed |