SCHEMBL9789569

SCHEMBL9789569

CCOC(OCC)C(F)C(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17264950 0.80 THRB (0.44) THRBLMNA
SCHEMBL1568155 0.78 THRB (0.57) THRBLMNA
SCHEMBL9026383 0.75 THRB (0.40) THRBLMNA
SCHEMBL17264952 0.75 THRB (0.40) THRBLMNA
SCHEMBL31296282 0.72 THRB (0.50) THRBLMNA
SCHEMBL2370384 0.72
SCHEMBL3419822 0.72
SCHEMBL12710174 0.69
SCHEMBL4094836 0.69 LMNA (0.53) THRBLMNA
SCHEMBL358984 0.69 LMNA (0.53) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992592-A 1-fluoro-1-halo-3,6-dioxabicyclo [4.1.0]heptane preparation, process and use RHONE-POULENC CHIMIE (FR) 1991-02-12 US disclosed