Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996194 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL5741244 | 0.81 | — | — | |
| SCHEMBL18839968 | 0.75 | — | — | |
| SCHEMBL5663532 | 0.75 | TSHR (0.37) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL28063285 | 0.74 | HCAR2 (0.36) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL6152662 | 0.74 | TSHR (0.36) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL32691366 | 0.73 | TSHR (0.43) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL32691321 | 0.73 | TSHR (0.43) | ALDH1A1TSHRHPGDTP53HIF1A | |
| SCHEMBL21632368 | 0.73 | — | — | |
| SCHEMBL27746463 | 0.73 | TSHR (0.40) | ALDH1A1TSHRHPGDTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283276-B2 | Coordination complex system comprising tautomeric ligands | UNIVERSITEIT VAN AMSTERDAM (NL) | 2012-10-09 | — | — | US | disclosed |
| EP-2220099-B1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | UNIV AMSTERDAM (NL) | 2012-06-27 | — | — | EP | disclosed |
| US-20110003959-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | UNIVERSITEIT VAN AMSTERDAM | 2011-01-06 | — | — | US | disclosed |
| EP-2220099-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | Universiteit van Amsterdam (NL) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065856-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | UNIVERSITEIT VAN AMSTERDAM (NL) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003959-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | XRN2, LIG1, H1-2 | ALDH1A1 2270/4885TSHR 2644/4885HPGD 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.