Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 11/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790635 | 0.76 | FDPS (1.00) | FDPSMAPTNPC1RAB9APOLB | |
| SCHEMBL9790646 | 0.75 | FDPS (0.97) | FDPSMAPTNPC1RAB9APOLB | |
| SCHEMBL9790861 | 0.75 | FDPS (0.58) | FDPSMAPTNPC1KMT2ARAB9A | |
| SCHEMBL9790727 | 0.73 | FDPS (0.61) | FDPSMAPTNPC1KMT2ARAB9A | |
| SCHEMBL8159160 | 0.72 | FDPS (0.63) | FDPSMAPTNPC1KMT2ARAB9A | |
| SCHEMBL12921530 | 0.71 | FDPS (0.53) | FDPSMAPTNPC1KMT2ARAB9A | |
| SCHEMBL9790662 | 0.71 | FDPS (0.80) | FDPSMAPTNPC1KMT2ARAB9A | |
| SCHEMBL9274997 | 0.70 | HMGCR (0.38) | MAPTRAB9APOLBKDM4EALDH1A1 | |
| SCHEMBL5359327 | 0.70 | NPC1 (0.52) | MAPTNPC1KMT2ARAB9AKDM4E | |
| SCHEMBL2777930 | 0.68 | FDPS (0.58) | FDPSMAPTNPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |