Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790635 | 0.98 | FDPS (1.00) | FDPSMAPTFDFT1NPC1RAB9A | |
| SCHEMBL9790662 | 0.88 | FDPS (0.80) | FDPSMAPTFDFT1NPC1RAB9A | |
| SCHEMBL9790685 | 0.75 | FDPS (0.61) | FDPSMAPTNPC1RAB9AHPGD | |
| SCHEMBL9790564 | 0.74 | FDPS (0.56) | FDPSMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13351522 | 0.73 | FDPS (0.59) | FDPSMAPTNPC1RAB9AHPGD | |
| SCHEMBL2777930 | 0.72 | FDPS (0.58) | FDPSMAPTNPC1RAB9AHPGD | |
| SCHEMBL9790602 | 0.72 | FDPS (0.57) | FDPSMAPTNPC1RAB9ASMN1; SMN2 | |
| Phosphonic Acid SCHEMBL9790670 | 0.72 | FDPS (0.54) | FDPSMAPTNPC1RAB9AHPGD | |
| SCHEMBL9790756 | 0.70 | FDPS (0.97) | FDPSNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9790607 | 0.69 | FDPS (0.96) | FDPSNPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |