Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977871 | 0.66 | GPR119 (0.53) | GPR119 | |
| SCHEMBL371712 | 0.64 | GPR119 (0.55) | GPR119KDM4EPKM | |
| SCHEMBL7367546 | 0.64 | GPR119 (0.57) | GPR119KDM4EPKM | |
| SCHEMBL27124589 | 0.63 | HPGD (0.47) | GPR119KDM4EPKM | |
| Hydrochloric Acid SCHEMBL1532657 | 0.63 | GNAI3 (0.53) | GPR119KDM4EPKM | |
| SCHEMBL3249170 | 0.63 | KDM4E (0.61) | GPR119KDM4EPKM | |
| SCHEMBL389015 | 0.63 | GPR119 (0.75) | GPR119 | |
| SCHEMBL15057744 | 0.63 | GABRP (0.31) | — | |
| SCHEMBL3096959 | 0.62 | GPR119 (0.67) | GPR119 | |
| SCHEMBL31690406 | 0.62 | HPGD (0.46) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207344-B2 | GPR119 agonists | ELI LILLY AND COMPANY (US) | 2012-06-26 | — | — | US | disclosed |
| US-20110015199-A1 | GPR119 Agonists | ELI LILLY AND COMPANY (US) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015199-A1 | GPR119 Agonists | GPR119, GLP1R, GCGR | GPR119 1/4885KDM4E 3038/4885PKM 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.