Phosphonic Acid

Phosphonic Acid

SCHEMBL9790757

O=P(O)(O)CNc1ncco1.O=[PH](O)O.[NaH].[NaH]

nearest known ligand 0.33

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
LRRK2 Q5S007 1/20 0.32
NAMPT P43490 1/20 0.32
PSMD14 O00487 1/20 0.32
STAMBP O95630 1/20 0.32
COPS5 Q92905 1/20 0.32
EPHX2 P34913 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL9790626 0.69 FDPS (0.51)
SCHEMBL9790706 0.68 FDPS (0.50)
Phosphonic Acid SCHEMBL9790611 0.67 SCD (0.47)
SCHEMBL4722379 0.64
Phosphonic Acid SCHEMBL9790775 0.64 FDPS (0.54)
Phosphonic Acid SCHEMBL9790670 0.61 FDPS (0.54)
SCHEMBL31213576 0.60 NUDT1 (0.39)
SCHEMBL2712690 0.59 GAA (0.55) CSNK2A2CSNK2BCSNK2A1CSNK2A3NAMPT
SCHEMBL8124745 0.59 NAMPT (0.60) CSNK2A2CSNK2BCSNK2A1CSNK2A3LRRK2
SCHEMBL3070030 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057505-A Treatment of illnesses attributed to calcium metabolism disorders CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed