Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 10/20 | 0.43 |
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL9790585 | 0.77 | MAPT (0.49) | MAPTNPC1RAB9AKMT2AMEN1 | |
| Phosphonic Acid SCHEMBL9790775 | 0.73 | FDPS (0.54) | FDPSNPC1RAB9AKMT2AMEN1 | |
| Phosphonic Acid SCHEMBL9790626 | 0.73 | FDPS (0.51) | FDPSNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9790646 | 0.72 | FDPS (0.97) | FDPSMAPTNPC1RAB9AGAA | |
| SCHEMBL9790635 | 0.70 | FDPS (1.00) | FDPSMAPTNPC1RAB9AGAA | |
| SCHEMBL12597147 | 0.69 | RAB9A (0.54) | FDPSMAPTNPC1RAB9AKMT2A | |
| SCHEMBL4097870 | 0.68 | MAPT (0.51) | FDPSMAPTNPC1RAB9AKMT2A | |
| SCHEMBL8302977 | 0.68 | — | — | |
| Phosphonic Acid SCHEMBL9790822 | 0.68 | ACP1 (0.56) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL424283 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |