SCHEMBL9790809

SCHEMBL9790809

COc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.67
SMN1; SMN2 Q16637 6/20 0.64
RAB9A P51151 1/20 0.63
ALDH1A1 P00352 3/20 0.62
HTT P42858 3/20 0.62
HPGD P15428 3/20 0.62
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C19 P33261 1/20 0.60
FFAR1 O14842 1/20 0.60
MAPT P10636 2/20 0.59
LIPE Q05469 1/20 0.59
POLB P06746 1/20 0.59
XBP1 P17861 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360493 0.94 SMN1; SMN2 (0.71) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL12585076 0.90 LMNA (0.64) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL11459158 0.89 SMN1; SMN2 (0.66) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL21652285 0.88 LMNA (0.65) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL5687596 0.87 RAB9A (0.73) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL2711491 0.87 SMN1; SMN2 (0.65) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL11196331 0.87 SMN1; SMN2 (0.67) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL31251923 0.87 RAB9A (0.73) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL10440879 0.86 RAB9A (0.72) LMNASMN1; SMN2RAB9AALDH1A1HTT
SCHEMBL6901995 0.86 SMN1; SMN2 (0.64) LMNASMN1; SMN2RAB9AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028870-B1 PHENOXYPYRIDINE COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-16 EP claimed
US-5068336-A Mixing hydroquinone with a dehydrohalogenation agent in an aprotic solvent and 2,3-dichloro-5-trifluoromethylpyridine to form an ether linkage TOSOH CORPORATION (JP) 1991-11-26 US disclosed
EP-0385720-A2 Process for producing 2-(4'-hydroxyphenoxy)-3-chloro-5-trifluoromethylpyridine Tosoh Corporation (JP) 1990-09-05 EP disclosed
US-4925947-A AGRICULTURAL USE, SENSITIVE TO CROPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-15 US disclosed
EP-0001473-B1 HERBICIDAL HALOGENOMETHYL--PYRIDYLOXY-PHENOXY-ALKANECARBOXYLIC ACIDS AND DERIVATIVES, AND PROCESSES OF CONTROLLING UNWANTED PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-27 EP disclosed
EP-0028870-B1 PHENOXYPYRIDINE COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-16 EP disclosed
EP-0003877-B1 HERBICIDAL DERIVATIVES OF 2-(4(2-PYRIDYLOXY)PHENOXY)PROPANE, PROCESSES FOR PREPARING THEM, AND HERBICIDAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-02-03 EP disclosed
US-4586953-A Herbicidal pyridyloxy phenoxy propanols or derivatives thereof herbicidal composition containing same and their herbicidal use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-05-06 US disclosed
US-4555575-A CHLORINATION OF A DISUBSTITUTED METHYL PYRIDINE HYDROCHLORIDE SALT IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-11-26 US disclosed
EP-0004414-B1 MIXTURES OF HERBICIDAL PYRIDYLOXYPHENOXYPROPANOIC ACID DERIVATIVES WITH OTHER HERBICIDES, AND PROCESSES OF KILLING UNWANTED PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-24 EP disclosed
US-4246419-A SULFONAMIDE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-20 US disclosed
EP-0021453-A2 2-Chloro-5-trichloromethylpyridine IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-07 EP disclosed
WO-1979000786-A1 HERBICIDAL COMPOUNDS ICI LTD (GB) 1979-10-18 WO disclosed
EP-0004414-A1 Mixtures of herbicidal pyridyloxyphenoxypropanoic acid derivatives with other herbicides, and processes of killing unwanted plants therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-03 EP disclosed
EP-0004433-A1 Herbicidal 2-(p-substituted-phenoxy)-pyridines and process for preparing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-03 EP disclosed
WO-1979000624-A1 HERBICIDAL DERIVATIVES OF 2-(4(2-PYRIDYLOXY)PHENOXY)PROPANE,PROCESSES FOR PREPARING THEM,AND HERBICIDAL COMPOSITIONS CONTAINING THEM ICI LTD (GB) 1979-09-06 WO disclosed
EP-0003877-A1 Herbicidal derivatives of 2-(4(2-pyridyloxy)phenoxy)propane, processes for preparing them, and herbicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-09-05 EP disclosed
EP-0003648-A2 4-Aryloxy-substituted phenoxypropionamide derivatives useful as herbicides, compositions containing them, and processes for making them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-22 EP disclosed
EP-0001473-A2 Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-04-18 EP disclosed
WO-1979000094-A1 HERBICIDAL PYRIDINE COMPOUNDS ICI LTD (GB) 1979-03-08 WO disclosed