Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360493 | 0.91 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL9790809 | 0.88 | LMNA (0.67) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL12585076 | 0.87 | LMNA (0.64) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL11459158 | 0.87 | SMN1; SMN2 (0.66) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL2711491 | 0.84 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL31251923 | 0.84 | RAB9A (0.73) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL11196331 | 0.84 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL5687596 | 0.84 | RAB9A (0.73) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL10440879 | 0.84 | RAB9A (0.72) | LMNASMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL6901995 | 0.83 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | LMNA 4658/4885SMN1; SMN2 1799/4885RAB9A 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.