Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791081 | 1.00 | LTB4R (0.39) | LTB4RLTB4R2HDAC6ALOX5GABRA1 | |
| SCHEMBL9790982 | 0.86 | ALOX5 (0.46) | LTB4RLTB4R2ALOX5PTGS2PTGS1 | |
| SCHEMBL9790978 | 0.86 | ALOX5 (0.46) | LTB4RLTB4R2ALOX5PTGS2PTGS1 | |
| SCHEMBL9790977 | 0.83 | ALOX5 (0.45) | HDAC6ALOX5PTGS2PTGS1 | |
| SCHEMBL9791043 | 0.82 | ALOX5 (0.48) | HDAC6ALOX5PTGS2 | |
| SCHEMBL9791045 | 0.82 | ALOX5 (0.48) | HDAC6ALOX5PTGS2 | |
| SCHEMBL9791205 | 0.81 | ALOX5 (0.45) | LTB4RHDAC6ALOX5PTGS2 | |
| SCHEMBL9791236 | 0.81 | ALOX5 (0.44) | LTB4RLTB4R2ALOX5PTGS2PTGS1 | |
| SCHEMBL9791231 | 0.81 | ALOX5 (0.44) | LTB4RLTB4R2ALOX5PTGS2PTGS1 | |
| SCHEMBL9791169 | 0.80 | ALOX5 (0.48) | LTB4RLTB4R2ALOX5PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |