Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 6/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.43 |
| ▸ | PTGFR | P43088 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791243 | 0.84 | ATG4B (0.55) | — | |
| SCHEMBL9791098 | 0.82 | PTGER3 (0.48) | PTGER3PTGER2PTGER4LTB4RLTB4R2 | |
| SCHEMBL9791103 | 0.82 | PTGER3 (0.48) | PTGER3PTGER2PTGER4LTB4RLTB4R2 | |
| Hydrochloric Acid SCHEMBL9791004 | 0.81 | PTGER3 (0.47) | PTGER3PTGER2PTGER4LTB4RLTB4R2 | |
| SCHEMBL3688787 | 0.77 | HDAC1 (0.62) | TAAR1CA1CA2CA4LMNA | |
| SCHEMBL3251665 | 0.76 | PTGER3 (0.64) | PTGER3PTGER2PTGER4TAAR1ALOX5 | |
| SCHEMBL16975581 | 0.75 | ALDH1A1 (0.61) | PTGER3PTGER2PTGER4LTB4RLTB4R2 | |
| SCHEMBL16975580 | 0.75 | ALDH1A1 (0.61) | PTGER3PTGER2PTGER4LTB4RLTB4R2 | |
| SCHEMBL9791064 | 0.74 | SMN1; SMN2 (0.51) | HDAC8HDAC1 | |
| SCHEMBL3105298 | 0.73 | HDAC1 (0.62) | TAAR1CA1CA2CA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |