Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 6/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791098 | 1.00 | PTGER3 (0.48) | PTGER3PTGER2TBXA2RPTGDRLTB4R | |
| Hydrochloric Acid SCHEMBL9791004 | 0.99 | PTGER3 (0.47) | PTGER3PTGER2TBXA2RPTGDRLTB4R | |
| SCHEMBL9791000 | 0.90 | BACE1 (0.41) | PTGER3PTGER2TBXA2RPTGDRLTB4R | |
| SCHEMBL9790996 | 0.90 | BACE1 (0.41) | PTGER3PTGER2TBXA2RPTGDRLTB4R | |
| SCHEMBL9790982 | 0.87 | ALOX5 (0.46) | LTB4RLTB4R2BACE1ALOX5 | |
| SCHEMBL9790978 | 0.87 | ALOX5 (0.46) | LTB4RLTB4R2BACE1ALOX5 | |
| SCHEMBL9791241 | 0.86 | ATG4B (0.51) | — | |
| SCHEMBL9791242 | 0.86 | ATG4B (0.51) | — | |
| Hydrochloric Acid SCHEMBL9791144 | 0.85 | ATG4B (0.50) | — | |
| SCHEMBL9791104 | 0.82 | PTGER3 (0.49) | PTGER3PTGER2TBXA2RPTGDRLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |