Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791140 | 1.00 | THRA (0.42) | THRATHRBKAT8PPARAATG4B | |
| SCHEMBL9791242 | 0.89 | ATG4B (0.51) | THRATHRBKAT8PPARAATG4B | |
| SCHEMBL9791241 | 0.89 | ATG4B (0.51) | THRATHRBKAT8PPARAATG4B | |
| Hydrochloric Acid SCHEMBL9791144 | 0.88 | ATG4B (0.50) | THRATHRBKAT8PPARAATG4B | |
| SCHEMBL9791000 | 0.85 | BACE1 (0.41) | — | |
| SCHEMBL9790992 | 0.84 | ALOX5 (0.41) | THRATHRBKAT8PPARAATG4B | |
| SCHEMBL9790994 | 0.84 | ALOX5 (0.41) | THRATHRBKAT8PPARAATG4B | |
| SCHEMBL9791110 | 0.80 | CDK1 (0.51) | THRATHRBKAT8PPARA | |
| SCHEMBL11765624 | 0.76 | THRA (0.54) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL6942269 | 0.76 | THRA (0.54) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |