Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792170 | 0.92 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL9792162 | 0.86 | — | — | |
| SCHEMBL9792183 | 0.77 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9792185 | 0.75 | BRD4 (0.47) | ALDH1A1 | |
| SCHEMBL9692155 | 0.71 | KDM4E (0.48) | — | |
| SCHEMBL9692272 | 0.70 | — | — | |
| SCHEMBL9792209 | 0.70 | — | — | |
| Water SCHEMBL10387452 | 0.69 | — | — | |
| SCHEMBL9792181 | 0.69 | GRIN1 (0.45) | ALDH1A1 | |
| SCHEMBL9693458 | 0.68 | GRIN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066654-A | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-11-19 | — | — | US | claimed |
| US-5066654-A | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-11-19 | — | — | US | disclosed |