SCHEMBL9792183

SCHEMBL9792183

Clc1ccc(-c2nc3ccc(Cl)nc3n2Cc2ccccn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9792181 0.92 GRIN1 (0.45) ALDH1A1
SCHEMBL9792178 0.89 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2
SCHEMBL9792182 0.88 BRD4 (0.51)
SCHEMBL9792175 0.79 GRIN1 (0.47) ALDH1A1SMN1; SMN2
SCHEMBL9792194 0.77 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2
SCHEMBL9792190 0.76 BRD4 (0.52) ALDH1A1
SCHEMBL9692155 0.72 KDM4E (0.48)
SCHEMBL9692272 0.71
Water SCHEMBL10387452 0.70
SCHEMBL9792170 0.69 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066654-A 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants A. H. ROBINS COMPANY, INCORPORATED (US) 1991-11-19 US claimed
US-5066654-A 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants A. H. ROBINS COMPANY, INCORPORATED (US) 1991-11-19 US disclosed