Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405782 | 0.88 | MEN1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14693827 | 0.88 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14205642 | 0.75 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26798520 | 0.75 | MAPT (0.64) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL13947209 | 0.75 | MAPT (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15426481 | 0.74 | L3MBTL1 (0.44) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14693909 | 0.74 | RAB9A (0.60) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL29506380 | 0.74 | POLB (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20985210 | 0.74 | POLB (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16140721 | 0.73 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066654-A | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-11-19 | — | — | US | disclosed |